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ezetimibe food interactions

Effect of Food on Oral Absorption Concomitant food administration high fat or non-fat meals had no effect on the extent of absorption of ezetimibe when administered as ZETIA 10-mg tablets. The information is not intended to cover all possible uses directions precautions drug interactions or adverse effects nor should it be construed to indicate that use of a.


Ezetimibe Simvastatin And Alcohol Food Interactions Drugs Com

Administration of a single 10-mg dose of ezetimibe in fasted adults resulted in peak plasma concentrations C max of 34-55 ngmL within 4-12 hours T max.

. Drug interactions are possible but studies have not shown that these statins increase exposure to ciclosporin. Ezetimibe is a beta-lactam that is azetidin-2-one which is substituted at 1 3 and 4 by p-fluorophenyl 3-p-fluorophenyl-3-hydroxypropyl and 4-hydroxyphenyl groups respectively the 3R3S4S enantiomer. The C max value of ezetimibe was increased by 38 with consumption of high fat meals. Ezetimibe and simvastatin is used together with a low-fat diet and other treatments to lower total cholesterol in adults and children who are at least 10 years old.

It is not known whether ezetimibe and simvastatin reduces your risk of heart disease. Zetia ezetimibe is a prescription drug used to treat certain types of high cholesterol in adults and children. 5 Food consumption has minimal effect on ezetimibe absorption but the C max is. Dosage form labeller route of administration and marketing period.

It is a member of azetidines an organofluorine compound and a beta-lactam. Moderate Alcohol Ethanol atorvastatin. Protease inhibitors and statins taken together may increase the blood. Ezetimibe and simvastatin may also be used for purposes not listed in this medication guide.

Here is what you need to know about the possible unsafe interactions between alcohol and common prescription and over-the-counter medications. You should limit the use of alcohol while being treated with these medications. Moderate Drug Interaction. Our datasets provide approved product information including.

It has a role as an anticholesteremic drug an antilipemic drug and an antimetabolite. Atorvastatin may cause liver problems and using it with substantial quantities of ethanol may increase that risk. 5 The C max of the major pharmacologically-active metabolite ezetimibe-glucuronide was 45-71 ngmL and its T max was 1-2 hours. Co-administration with grapefruit products may increase the risk for adverse effects such as myalgia.

Drug product information from 10 global regions. ZETIA can be administered with or without food. Victoria Gnatiuk Getty Images Why Medications and Alcohol Dont Mix. The absolute bioavailability cannot be determined since ezetimibe.

Find patient medical information for ezetimibe oral on WebMD including its uses side effects and safety interactions pictures warnings and user ratings. Call your doctor immediately if you have. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Distribution Ezetimibe and ezetimibe.

Food and Drug Administration FDA notified healthcare professionals of updates to the prescribing information concerning interactions between protease inhibitors and certain statin drugs. According to the National Institute on Alcohol Abuse and Alcoholism NIAAA there are several reasons that it can be harmful to mix. However coadministration with a high-fat meal increases its C max by 38. The concomitant administration of food high-fat vs.

Learn about side effects dosage and more. Nonfat meals has no effect on the extent of absorption of ezetimibe. There are 2 alcoholfoodlifestyle interactions with atorvastatin which include.


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